Application
FACS analysis of human peripheral blood granulocytes using IGF1R antibody [1H7] (Low endotoxin, azide free).| Product Name | IGF1R antibody [1H7] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [1H7] to IGF1 ReceptorThis receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008] |
| Immunogen | Purified human placental IGF1 receptor |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 1H7 |
| Host Species | Mouse |
| Tested Applications | FACSIHC-PWBFunctional Assay |
| Flow Cytometry: Max Dilution 1/10 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | IGFIR , IGFR , IGF1R , JTK13 , CD221 |
|---|---|
| Target | IGF1R |
| Tissue Specificity | This antibody recognizes an epitope in IGF1 Receptor. Clone 1H7 is reported to partically block binding of IGF-I and IGF-II to IGF1 Receptor (Li et al.1993). |
Application
FACS analysis of human peripheral blood granulocytes using IGF1R antibody [1H7] (Low endotoxin, azide free).| Application Notes | Flow Cytometry: Max Dilution 1/10 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C only. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline |
