Mouse monoclonal antibody [3G5C1] to IGF1RThis receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008]
Immunogen
The immunogen corresponding to IGF1R expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
3G5C1
Host Species
Mouse
Tested Applications
ELISAIHCIHC-PWB
ELISA: 1/10000.
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
JTK13 , CD221 , IGFR , IGFIR
Target
IGF1R
Molecular Weight(MW)
96 kDa (note)
Application
Application
Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using IGF1R-Beta mouse mAb with DAB staining
Application
Western blot analysis using anti-IGF1R monoclonal antiobdy against truncated IGF1R recombinant protein.
Application Notes
ELISA: 1/10000.
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.