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IL1 beta antibody

Catalog Number:OM258658
OM258658
Discount Price
OM258658-100ul
1~2 Week
100ul
OM258658-50ul
50ul
1~2 Week
Product Profile
Product Name IL1 beta antibody
Antibody Type Primary Antibodies
Product description Mouse monoclonal antibody [3A6] to IL1 betaThe protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
Immunogen The immunogen corresponding to human IL1B expressed in E. Coli.
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number 3A6
Host Species Mouse
Tested Applications ELISAICC/IFIHCIHC-PWB
ELISA: 1/10000.:
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms IL-1
IL1B
IL1F2
IL1-BETA
Target IL1 beta
Molecular Weight(MW) 31 kDa (note)
Application

Application

WB analysis of human IL1 beta recombinant protein (aa. 126-261) using IL1 beta antibody [3A6].

Application

WB analysis of lysates from (1) HEK293 and (2) IL1B-hIgGFc transfected HEK293 cells using IL1 beta antibody [3A6].

Application

IHC-P analysis of muscle tissues using IL1 beta antibody [3A6].

Application

IHC-P analysis of lung cancer tissues using IL1 beta antibody [3A6].

Application

ICC/IF analysis of HepG2 cells using IL1 beta antibody [3A6] (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Application

ELISA analysis of control antigen and antigen using IL1 beta antibody [3A6].
Application Notes ELISA: 1/10000.:
Additional Information
Form Liquid
Storage Instructions 4°C; -20°C for long term storage
Storage Buffer Ascitic fluid containing 0.03% sodium azide.
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