Sandwich ELISA analysis of human IL1 beta using IL1 beta antibody [ILB1-H67] as a capture reagent and IL1 beta antibody [ILB1-H6] (Biotin) as a detection reagent.
Mouse monoclonal antibody [ILB1-H67] to IL1 betaThe protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant human IL-1 beta
Key Feature
Clonality
Monoclonal
Isotype
IgG2
Clone Number
ILB1-H67
Host Species
Mouse
Tested Applications
ELISAWB
Recommended Starting Dilutions: ELISA: 1 ug/ml. Pair for sandwich ELISA: GTX15756 for capture antibody, and GTX15755 for detection antibody. Optimal dilution / concentration should be determined by the end user.:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Protein G
Target Information
Gene Synonyms
IL1F2 IL-1 interleukin 1 beta IL1B IL1-BETA
Target
IL1 beta
Application
Application
Sandwich ELISA analysis of human IL1 beta using IL1 beta antibody [ILB1-H67] as a capture reagent and IL1 beta antibody [ILB1-H6] (Biotin) as a detection reagent.
Application Notes
Recommended Starting Dilutions: ELISA: 1 ug/ml. Pair for sandwich ELISA: GTX15756 for capture antibody, and GTX15755 for detection antibody. Optimal dilution / concentration should be determined by the end user.: