Application
Application| Product Name | IL1 beta antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [S1H12] to IL1 betaInterleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence. |
| Immunogen | Recombinant full length protein (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | S1H12 |
| Host Species | Mouse |
| Tested Applications | ELISAWB |
| ELISA: Use at an assay dependent dilution. WB: Use at a concentration of 0.02 - 0.1 μg/ml. Predicted molecular weight: 30 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Protein G |
| Gene Synonyms | Catabolin antibody H1 antibody Hematopoietin 1 antibody IFN beta inducing factor antibody IL-1 antibody IL1 beta antibody IL1-BETA antibody IL1B antibody IL1F2 antibody Interleukin 1 beta precursor antibody OAF antibody Osteoclast act |
|---|---|
| Target | IL1 beta |
| Tissue Specificity | Does not show any cross reaction with recombinant human IL-1α, recombinant murine IL-1α or IL-1β. |
| Cellular Localization | Secreted |
| Light Chain Type | kappa |
Application
Application| Application Notes | ELISA: Use at an assay dependent dilution. WB: Use at a concentration of 0.02 - 0.1 μg/ml. Predicted molecular weight: 30 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: None. Constituents: 0.01M PBS. pH 7.2 |
