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IL10 antibody

Catalog Number:OM258695
OM258695
Discount Price
OM258695-100ul
1~2 Week
100ul
OM258695-50ul
50ul
OM258695-20ul
20ul
1~2 Week
Product Profile
Product Name IL10 antibody
Antibody Type Primary Antibodies
Product description Rabbit polyclonal antibody to IL10The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISAIHC-PWB
P-ELISA:1:500-1000, WB:1:100-500, IHC-P:1:100-500 (based on 0.5 mg/ml):
Species Reactivity HumanMouseDogPigRat
Concentration 0.5mg/ml
Purification Affinity purified
Target Information
Gene Synonyms CSIF
interleukin 10
IL-10
IL10A
TGIF
GVHDS
Target IL10
Application

Application

IHC-P analysis of dog ureter tissue using IL-10 antibody.

Application

IHC-P analysis of human colon tissue using IL-10 antibody.
Application Notes P-ELISA:1:500-1000, WB:1:100-500, IHC-P:1:100-500 (based on 0.5 mg/ml):
Additional Information
Form Liquid
Storage Instructions Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Storage Buffer 10 mM PBS, pH 7.4 with 10 mg/ml BSA and 0.1% sodium azide
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