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Anti-IL10 antibody

Catalog Number:OM680635
OM680635
Discount Price
OM680635-100ul
100ul
Product Profile
Product Name Anti-IL10 antibody
Antibody Type Primary Antibodies
Immunogen Recombinant mouse IL10 protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Mouse
Tested Applications ELISA
ELISA:1:1000
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol IL10
Gene Synonyms CSIF
TGIF
GVHDS
IL-10
IL10A
Gene Full Name interleukin 10
Gene Summary The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2020]
Application

ELISA

5.0-10.0 μg/ml of this antibody will detect at least 1000 pg/well of recombinant Mouse IL-10. As the detection antibody at a concentration of approximately 0.5-1.0 μg/ml.
Application Notes ELISA:1:1000
Additional Information
Form Liquid
Storage Instructions Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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