5.0-10.0 μg/ml of this antibody will detect at least 1000 pg/well of recombinant Mouse IL-10. As the detection antibody at a concentration of approximately 0.5-1.0 μg/ml.
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2020]
Application
ELISA
5.0-10.0 μg/ml of this antibody will detect at least 1000 pg/well of recombinant Mouse IL-10. As the detection antibody at a concentration of approximately 0.5-1.0 μg/ml.
Application Notes
ELISA:1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Storage Buffer
Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.