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IL10 antibody

Catalog Number:OM258699
OM258699
Discount Price
OM258699-100ul
1~2 Week
100ul
OM258699-50ul
50ul
OM258699-20ul
20ul
1~2 Week
Product Profile
Product Name IL10 antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to IL10The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
Immunogen Recombinant protein of human IL10.
Modification Acetylated
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IFIHCWB
Western blotting: 1:500 - 1:2000:
Species Reactivity HumanMouseRat
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified
Target Information
Gene Synonyms interleukin 10
CSIF
IL10A
GVHDS
TGIF
Target IL10
Tissue Specificity The antibody detects endogenous level of total IL10 antibody.
Application

Application

IL10 antibody detects IL10 protein by western blot analysis. Various whole cell extracts (40 μg) were separated, and the membrane was blotted with IL10 antibody diluted by 1:1000.

Application

IHC-P analysis of rat kidney, using IL10 antibody at 1:100 dilution.
Application Notes Western blotting: 1:500 - 1:2000:
Additional Information
Form Liquid
Storage Instructions Store at -20˚C
Storage Buffer Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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