| Product Name | IL12 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [1-1A4] to IL12 p40IL12 is a heterodimeric cytokine comprised of p35 and p40 subunits. IL12 plays a central role in mediating cell mediated immunity, promoting differentiation of CD4+ T cells to the Th1 subset and of CD8+ T cells into mature cytotoxic T lymphocytes (CTLs). IL12 is a potent stimulator of NK cells. IL12 therapy has been suggested as a method of enhancing cytocidal anti tumour immune responses. |
| Immunogen | Recombinant human interleukin-12 produced in Baculovirus. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 1-1A4 |
| Host Species | Mouse |
| Tested Applications | ELISAIHC-FRIA |
| For ELISA: Use at an assay dependent concentration. For RIA: Use at an assay dependent concentration. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Subunit P40 Natural Killer Cell Stimulatory Factor2 Natural Killer Cell Stimulatory Factor 2 Interleukin 12B 40 kD Subunit Cytotoxic lymphocyte maturation factor 40 kDa subunit T cell stimulating factor Cytotoxic lymphocyte maturation factor40 kDa s |
|---|---|
| Target | IL12 |
| Tissue Specificity | Recognises p35/40 heterodimer and p40. Used against CCHO and Baculovirus derived recombinant IL-12. Reacts with stimulated and unstimulated monocytes. |
| Cellular Localization | Secreted |
| Application Notes | For ELISA: Use at an assay dependent concentration. For RIA: Use at an assay dependent concentration. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline, pH 7.2, no preservative added |
