| Product Name | IL16 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [323] to IL16IL16, also known as lymphocyte chemoattractant factor (LCF), is a proinflammatory cytokine that is chemotactic for CD4+ T lymphocytes, monocytes, and eosinophils. IL16 is synthesized as a precursor molecule (pro IL16) of approximately 68 kDa and 631 amino acid residues lacking a signal peptide. The sequence and structure of IL16 is conserved across species. In addition to inducing chemotaxis, IL16 upregulates the IL2 receptor and upregulates HLADR expression. It also inhibits T cell receptor (TCR)/CD3 dependent activation, and suppresses HIV1 replication in vitro. Sources of IL16 include epithelial cells, mast cells, T lymphocytes (CD4+ and CD8+), macrophages, synovial fibroblasts, and eosinophils. |
| Immunogen | Recombinant full length protein (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | 323 |
| Host Species | Mouse |
| Tested Applications | ELISA |
| ELISA: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Protein G |
| Gene Synonyms | HsT19289 IL16 LCF HGNC:5980 PrIL16 Lymphocyte chemoattractant factor Interleukin 16 precursor Interleukin16 precursor FLJ16806 FLJ42735 FLJ44234 NIL16 prIL-16 prIL 16 |
|---|---|
| Target | IL16 |
| Tissue Specificity | exhibits no detectable cross-reacting with human albumin serum, Bovine albumin serum and other human cytokines or growth factors tested such as IL-1-beta, IL-8, IL-7 MCAF, TGF-beta-1, EGF, bFGF, GM-CSF, M-CSF, TNF-alpha. |
| Cellular Localization | Secreted |
| Light Chain Type | kappa |
| Application Notes | ELISA: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: None. Constituents: 0.01M PBS. pH 7.2 |
