| Product Name | IL17 Receptor beta antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [5P14] to IL-17B RThe protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008] |
| Immunogen | Human recombinant IL-17B R EC domain |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 5P14 |
| Host Species | Mouse |
| Tested Applications | FACSWB |
| WB(1:500-1000)|Neutralization of IL-17D-receptor binding: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | IL17RB IL17RH1 interleukin 17 receptor B IL17BR EVI27 CRL4 |
|---|---|
| Target | IL-17B R |
| Tissue Specificity | This antibody was selected for its ability to detect human IL-17B R. |
| Application Notes | WB(1:500-1000)|Neutralization of IL-17D-receptor binding: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
