| Product Name | IL2 Receptor alpha antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [1X27] to CD25The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009] |
| Immunogen | Human recombinant IL-2 R alpha EC domain |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 1X27 |
| Host Species | Mouse |
| Tested Applications | IHCNeutWB |
| WB(1:500-2000)|Neutralization of IL-2R alpha signaling|IHC (paraffin)(1:20-100): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CD25 IL2RA IDDM10 IL2R interleukin 2 receptor alpha TCGFR |
|---|---|
| Target | IL-2R alpha |
| Tissue Specificity | This antibody was selected for its ability to detect human CD25 |
| Application Notes | WB(1:500-2000)|Neutralization of IL-2R alpha signaling|IHC (paraffin)(1:20-100): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
