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IL21 Receptor antibody

Catalog Number:OM259031
OM259031
Discount Price
OM259031-100ul
1~2 Week
100ul
OM259031-50ul
50ul
OM259031-20ul
20ul
1~2 Week
Product Profile
Product Name IL21 Receptor antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to IL21-RThe protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
Immunogen IL-21 receptor antibody was raised against a synthetic peptide corresponding to amino acids 97 to 111 of human IL-21 receptor precursor.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISAICC/IFIHC-PWB
IF: 20 ug/mL:
Species Reactivity HumanRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms IL21R
NILR
CD360
interleukin 21 receptor
Target IL21-R
Application

Application

Western blot analysis of IL-21 receptor expression in human Raji cell lysate with IL-21 Receptor antibody at 1 ug /ml.

Application

Immunohistochemistry of IL-21 receptor in rat lung with IL-21 receptor antibody at 10 ug/mL.

Application

Immunofluorescence of IL-21 Receptor in Rat Lung cells with IL-21 Receptor antibody at 20 ug/mL.
Application Notes IF: 20 ug/mL:
Additional Information
Form Liquid
Storage Instructions Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer PBS containing 0.02% sodium azide.
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