| Product Name | IL24 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [6F48] to IL-24This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| Immunogen | Human recombinant IL-24 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 6F48 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB(1:500-2000): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ST16 MDA7 IL24 MOB5 C49A FISP interleukin 24 IL10B |
|---|---|
| Target | IL-24 |
| Tissue Specificity | This antibody was selected for its ability to detect human IL-24. |
| Application Notes | WB(1:500-2000): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
