Rabbit polyclonal to IL-27/IL-30Recently, a new heterodimeric cytokine termed IL-27 that consists of EBI3 (Epstein-Barr virus-induced gene 3), an IL-12p40-related protein, and p28, a newly discovered IL-12p35-related polypeptide has been discovered. IL-27 is involved in early Th1 initiation. Its action is mediated through the orphan cytokine receptor WSX-1/TCCR and gp130. IL-27 may also play a role in the induction of T-bet expression and regulation of Ig class switching in B cells.
Immunogen
A synthetic peptide from amino acids 20-70 region of Genbank accession number NP_663634 was used as immunogen. The immunogen is 100% identical with mouse sequence.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: Use at 1:500-1:1000:
Species Reactivity
HumanMouse
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
IL-27 IL-27p28 Il30 p28 IL 27 IL 27p28 IL27 IL27p28
Target
IL27+ IL30
Application
Application
Western blot analysis of IL-27 in (A) Jurkat and (B) NIH 3T3 cells using at 1 ug/ml.
Positive Control
Jurkat and NIH 3T3 cell lysates
Application Notes
WB: Use at 1:500-1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4°C, stable for 6 months. For long-term storage, store at -20°C.
Storage Buffer
PBS containing 0.2% gelatin and 0.05% sodium azide.