Rabbit polyclonal antibody to TCCRIn mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. [provided by RefSeq, Jul 2008]
Immunogen
A peptide corresponding to amino acids near the carboxy terminus of human IL-27R alpha precursor.
This antibody recognizes the carboxy terminal of the alpha subunit of the human IL-27 receptor, otherwise known as the T cell cytokine receptor (TCCR).
Application
Application
IHC analysis of human spleen tissue using IL27 Receptor alpha antibody.
Application
WB analysis of human spleen tissue lysate using IL27 Receptor alpha antibody.
Application Notes
Immunofluorescence: 20 ug/ml:
Additional Information
Form
Liquid
Storage Instructions
Store at +4oC or at -20oC if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.