Rabbit polyclonal antibody to ILP-2ILP-2 (for IAP-like protein-2) is a novel member of in the IAP (Inhibitor of Apoptosis) protein family. ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues. ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibit apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Western blotting (0.5-4 µg/ml). However, the optimal dilution conditions should be determined individually. The affinity-purified rabbit antibody recognizes ~32 kDa ILP-2 in samples from human, mouse and rat origins.:
Species Reactivity
HumanMouseRat
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
IAP like protein 2 hILP 2 BIRC8 ILP2 hILP2 BIRC 8 BIRC-8 IAP like protein2 ILP-2 ILP 2
Target
ILP-2
Tissue Specificity
This antibody is specific for ILP-2.
Application
Application
Western blot analysis of ILP-2 expression in 3T3 cell lysate.
Application Notes
Western blotting (0.5-4 µg/ml). However, the optimal dilution conditions should be determined individually. The affinity-purified rabbit antibody recognizes ~32 kDa ILP-2 in samples from human, mouse and rat origins.:
Additional Information
Form
Liquid
Storage Instructions
The antibody solution should be gently mixed before use. Stored at -20 °C for future use.