| Product Name | INK4c antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to p18 INK4c - BSA and Azide freep18 INK4c is a specific inhibitor of cdk4 / cdk6 and is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S phase. |
| Immunogen | Recombinant full length protein (Expressed in E. coli). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIP |
| IF: Use at an assay dependent dilution. IP: Use at 10μg/mg of lysate with Protein A Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Protein A |
| Gene Synonyms | CDK6 inhibitor p18 CDKN2C CDKN6 CDN6 Cyclin dependent inhibitor Cyclin dependent kinase 4 inhibitor C Cyclin dependent kinase 6 inhibitor p18 Cyclin dependent kinase 6 inhibitor p18 INK6 Cyclin dependent kinase inhibitor 2C Highly similar to cyclin depende |
|---|---|
| Target | INK4c |
| Tissue Specificity | shows no cross reaction with the closely related inhibitors such as p15 INK4b and p16 INK4a. The antibody does cross react with p19 INK4d. |
| Cellular Localization | Nuclear |
| Positive Control | HeLa, CEM, ML-1, C2 or 3T3-L1 whole cell lysate |
|---|---|
| Application Notes | IF: Use at an assay dependent dilution. IP: Use at 10μg/mg of lysate with Protein A Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: NoneConstituents: 10mM PBS. pH 7.4 |
