| Product Name | INK4c antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to p18 INK4cp18 INK4c is a specific inhibitor of cdk4 / cdk6 and is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S phase. |
| Immunogen | Synthetic peptide conjugated to KLH - C terminal amino acids 155-168 of human p18 INK4c. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIPWB |
| For IF: Use at an assay dependent dilution. For IP: (Co-precipitates cdk4/cdk6) (Use Protein A, 10ug/mg protein lysate) For WB: Use at a concentration of 5-10 μg/ml for 2hrs at RT. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | CDK6 inhibitor p18 CDKN2C CDKN6 CDN6 Cyclin dependent inhibitor Cyclin dependent kinase 4 inhibitor C Cyclin dependent kinase 6 inhibitor p18 Cyclin dependent kinase 6 inhibitor p18 INK6 Cyclin dependent kinase inhibitor 2C Highly similar to cyclin depende |
|---|---|
| Target | INK4c |
| Cellular Localization | Nuclear |
| Application Notes | For IF: Use at an assay dependent dilution. For IP: (Co-precipitates cdk4/cdk6) (Use Protein A, 10ug/mg protein lysate) For WB: Use at a concentration of 5-10 μg/ml for 2hrs at RT. Optimal dilutions/concentrations should be determined by the researcher.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | 10mM Phosphate-buffered saline, pH 7.4 |
