| Product Name | Insulin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [C7C9] to InsulinInsulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage,formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B or b-cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma. |
| Immunogen | Full length native protein (purified) |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | C7C9 |
| Host Species | Mouse |
| Tested Applications | ELISA |
| ELISA: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanPigBovine |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Target | Insulin |
|---|---|
| Tissue Specificity | This antibody reacts with c-terminal pentapeptide of insulin beta-chain. Kass for this antibody is 1.0 x 10 9 M-1. It cross-reacts with human proinsulin, no cross-reaction with free C-peptide. |
| Cellular Localization | Secreted |
| Light Chain Type | kappa |
| Application Notes | ELISA: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. We recommend to parafilm vials during storage to prevent evaporation of buffer. |
| Storage Buffer | Phosphate-buffered saline, pH 7.4, containing 0.1% sodium azide |
