| Product Name | Integrin alpha 2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [Gi9] to Integrin alpha 2This antibody inhibits the adhesion of platelets to collagen. |
| Immunogen | Tissue / cell preparation (isolated human platelets). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | Gi9 |
| Host Species | Mouse |
| Tested Applications | ELISAFACSIMFunctional Assay |
| ELISA: Use at an assay dependent dilution. FACS: Use 2μg for 5 x 10^6 platelets. IM: Use 2μg for 5 x 10^6 platelets. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Purification | Protein G |
| Gene Synonyms | CD49b VLA2 alpha chain Collagen receptor Integrin alpha 2 Integrin alpha2 BR CD49B GPIa VLA-2 VLAA2 VLA 2 VLA2 |
|---|---|
| Target | Integrin alpha 2 |
| Tissue Specificity | This antibody recognises the VLA2 antigen (alpha 2 beta 1 complex) also called Ia/IIa glycoprotein complex or collagen receptor. It reacts with the molecules carrying the Br(a) as well as the Br(b) alloantigen. It reacts with platelets, megakaryocytes and activated T cells. Does not react with B lymphocytes, T lymphocytes, monocytes, granulocytes and red blood cells. The molecular weight of the recognized antigen is 138/115kDa under non-reducing conditions and 145/126kDa under reducing conditions. |
| Cellular Localization | Cell Membrane |
| Light Chain Type | kappa |
| Application Notes | ELISA: Use at an assay dependent dilution. FACS: Use 2μg for 5 x 10^6 platelets. IM: Use 2μg for 5 x 10^6 platelets. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: None. Constituents: PBS, 1mg/ml BSA |
