| Product Name | IRS1 (phospho Ser616) antibody [HIR-B1] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [HIR-B1] to IRS (phospho-Ser616)Insulin receptor substrates (IRS) subtypes are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. The balance between Ser/Thr phosphorylation of IRS has been demonstrated to be an important regulator of insulin signaling. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm’s tumors, and adrenal cortical carcinomas. Does not recognize IRS peptide NOT phosphorylated at Ser616 and will not recognize IRS peptide phosphorylated at Tyr183. Also does not react with riboflavin carrier protein which is known to have multiple phosphate groups. |
| Modification | p-Ser616 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | HIR-B1 |
| Host Species | Mouse |
| Tested Applications | ELISAWB |
| The antibody can be used for indirect ELISA and WB. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | phosphoIRS (phosphoSer616) (pS616), IRS, PhosphoIRS (Ser616), phosphoIRS (phosphoSer616) (pSer616), phospho IRS (phospho-Ser616) (pS616), phospho-IRS (phospho-Ser616) (pSer616), phospho-IRS (phospho-Ser616) (pS616), phospho IRS, phospho IRS (phosphoSer616) |
|---|---|
| Target | IRS (phospho-Ser616) (phospho Ser616) |
| Tissue Specificity | This antibody is specific for IRS (phospho-Ser616) (phospho Ser616). |
| Application Notes | The antibody can be used for indirect ELISA and WB. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS with 0.05% (W/V) sodium azide |
