Application
Western blot analysis of extracts of various cell lines, using COPS5 antibody.Application
Immunohistochemistry of paraffin-embedded rat kidney using COPS5 antibody at dilution of 1:100 (x400 lens).Application
Immunohistochemistry of paraffin-embedded human liver using COPS5 antibody at dilution of 1:100 (x400 lens).Application
Immunofluorescence analysis of HeLa cell using COPS5 antibody. Blue: DAPI for nuclear staining.| Product Name | JAB1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to JAB1The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant protein of human COPS5 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCIHC-PWB |
| WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | MOV34 CSN5 COP9 signalosome subunit 5 COPS5 SGN5 |
|---|---|
| Target | JAB1 |
Application
Western blot analysis of extracts of various cell lines, using COPS5 antibody.
Application
Immunohistochemistry of paraffin-embedded rat kidney using COPS5 antibody at dilution of 1:100 (x400 lens).
Application
Immunohistochemistry of paraffin-embedded human liver using COPS5 antibody at dilution of 1:100 (x400 lens).
Application
Immunofluorescence analysis of HeLa cell using COPS5 antibody. Blue: DAPI for nuclear staining.| Application Notes | WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
