Rabbit polyclonal antibody to JIKInhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IPWB
Western blotting (1:500 – 1:2500) and Immunoprecipitation. However, the optimal concentrations should be determined individually. The antibody recognizes the JIK/TAOK3 of human and mouse origins. Reactivity to other species has not been tested.:
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
TAO Kinase 3 TAOK3 TAO Kinase3 DPK JIK JNK/SAPK-Inhibitory Kinase Dendritic cell derived protein kinase MAP3K18 JNK/SAPKInhibitory Kinase JNK/SAPK Inhibitory Kinase
Target
JIK
Tissue Specificity
This antibody is specific for JIK.
Cellular Localization
Also localized to the peripheral cell membrane.
Application Notes
Western blotting (1:500 – 1:2500) and Immunoprecipitation. However, the optimal concentrations should be determined individually. The antibody recognizes the JIK/TAOK3 of human and mouse origins. Reactivity to other species has not been tested.:
Additional Information
Form
Liquid
Storage Instructions
The antibody solution should be gently mixed before use. Stored at -20 °C for future use.