Rabbit polyclonal to JNK2c-Jun amino terminal kinases (JNKs) are MAP kinase family members that differ from other MAP kinases in that they are phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.
Immunogen
Synthetic peptide: AAVSSNATPSQ, corresponding to amino acids 379-389 of Human JNK2.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: Use at a concentration of 1 - 3 μg/ml. Predicted molecular weight: 51 kDa. Optimal dilutions/concentrations should be determined by the end user.: