Application
WB analysis of extracts from various tissues using JNK3 antibody.Application
IHC-P analysis of human esophageal cancer using JNK3 antibody at a dilution of 1:200.Application
IHC-P analysis of human stomach using JNK3 antibody at a dilution of 1:200.Application
IHC-P analysis of mouse kidney using JNK3 antibody at a dilution of 1:200.| Product Name | JNK3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to JNK3The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant protein of human MAPK10 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-PWB |
| WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. ICC: 1:50 - 1:200: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | JNK3A PRKM10 p493F12 SAPK1b MAPK10 p54bSAPK mitogen-activated protein kinase 10 |
|---|---|
| Target | JNK3 |
| Molecular Weight(MW) | 36 kDa (note) |
Application
WB analysis of extracts from various tissues using JNK3 antibody.
Application
IHC-P analysis of human esophageal cancer using JNK3 antibody at a dilution of 1:200.
Application
IHC-P analysis of human stomach using JNK3 antibody at a dilution of 1:200.
Application
IHC-P analysis of mouse kidney using JNK3 antibody at a dilution of 1:200.| Application Notes | WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. ICC: 1:50 - 1:200: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
