Application
IHC-P analysis of human heart tissue using KCNN3 antibody at 1:600. Left to right:DAPI, KCNN3, Merge. Low pH, heat-induced antigen retrieval method utilizing Sodium Citrate buffer.Application
WB analysis of Daudi cells using KCNN3 antibody at 0.2-1μg/ml.Application
IHC-P analysis of Rhesus macaque spinal cord tissue using KCNN3 antibody at 1:300.Application
WB analysis of mouse brain and kidney tissue using KCNN3 antibody at 2μg/ml. Lane l : Mouse kidney (negative control) Lane 2: Mouse whole brain (positive control)| Product Name | KCNN3 antibody, C-term |
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| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to KCNN3Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011] |
| Immunogen | A synthetic peptide corresponding to a C-terminal region of Human KCNN3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | HumanMouseRhesus Monkey |
| Predicted Reactivity | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | HSK3 SK3 KCNN3 SKCA3 KCA2.3 |
|---|---|
| Target | KCNN3 |
| Molecular Weight(MW) | 82 KDa (note) |
Application
IHC-P analysis of human heart tissue using KCNN3 antibody at 1:600. Left to right:DAPI, KCNN3, Merge. Low pH, heat-induced antigen retrieval method utilizing Sodium Citrate buffer.
Application
WB analysis of Daudi cells using KCNN3 antibody at 0.2-1μg/ml.
Application
IHC-P analysis of Rhesus macaque spinal cord tissue using KCNN3 antibody at 1:300.
Application
WB analysis of mouse brain and kidney tissue using KCNN3 antibody at 2μg/ml. Lane l : Mouse kidney (negative control) Lane 2: Mouse whole brain (positive control)| Positive Control | Daudi , mouse brain |
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| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
