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KCNQ1 antibody

Catalog Number:OM260444
OM260444
Discount Price
OM260444-100ul
1~2 Week
100ul
OM260444-50ul
50ul
1~2 Week
Product Profile
Product Name KCNQ1 antibody
Antibody Type Primary Antibodies
Product description Mouse Monoclonal Antibody [5E12] to KCNQ1This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
Immunogen The immunogen corresponding to human KCNQ1 expressed in E. Coli.
Key Feature
Clonality Monoclonal
Isotype IgG2
Clone Number 5E12
Host Species Mouse
Tested Applications ELISAFACSWB
ELISA: 1/10000.:
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms KV7.1
ATFB1
KCNA9
JLNS1
LQT1
LQT
SQT2
KVLQT1
ATFB3
WRS
RWS
KV1.9
KCNA8
Target KCNQ1
Molecular Weight(MW) 95 kDa (note)
Application

Application

ELISA analysis of control antigen and antigen using KCNQ1 antibody [5E12].

Application

FACS analysis of MCF-7 cells using KCNQ1 antibody [5E12] (green) or a negative control (red).

Application

WB analysis of (1) MCF-7 and (2) A431 lysates using KCNQ1 antibody [5E12].

Application

WB analysis of human KCNQ1 (a.a. 229-347) recombinant protein using KCNQ1 antibody [5E12].
Application Notes ELISA: 1/10000.:
Additional Information
Form Liquid
Storage Instructions 4°C; -20°C for long term storage
Storage Buffer Ascitic fluid containing 0.03% sodium azide.
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