Application
Western blot analysis of Kir2.1 in COS transient cells using a 1:1000 dilution ofApplication
IF analysis of Kir2.1 in mouse backskin sections.| Product Name | Kir2.1 antibody [S112B-14] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [S112B-14] to Kir2.1Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium. |
| Immunogen | Fusion protein amino acids 41-64 and 189-428 of mouse Kir2.1, accession number NP_032451. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | S112B-14 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHCWB |
| We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF). | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Protein G |
| Gene Synonyms | IRK1, HIRK1, HHBIRK1, KCNJ2, SQT3, HIRK 1, HHIRK1, LQT7, potassium inwardly rectifying channel J2 |
|---|---|
| Target | Kir2.1 |
| Molecular Weight(MW) | 45kDa (note) |
| Tissue Specificity | No cross-reactivity against Kir2.2 or Kir2.3 |
Application
Western blot analysis of Kir2.1 in COS transient cells using a 1:1000 dilution of
Application
IF analysis of Kir2.1 in mouse backskin sections.| Application Notes | We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF). |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20 C. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | PBS pH7.4, 50% glycerol |
