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Ku80 antibody [5C5]

Catalog Number:OM260951
OM260951
Discount Price
OM260951-100ul
1~2 Week
100ul
OM260951-50ul
50ul
1~2 Week
Product Profile
Product Name Ku80 antibody [5C5]
Antibody Type Primary Antibodies
Product description Mouse Monoclonal Antibody [5C5] to XRCC5The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Immunogen The immunogen corresponding to human XRCC5 expressed in E. Coli.
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number 5C5
Host Species Mouse
Tested Applications ELISAFACSICC/IFIHCIHC-PWB
ELISA: 1/10000.
Species Reactivity HumanMouse
Concentration 1mg/ml
Target Information
Gene Synonyms KU86 , KUB2 , KARP1 , KARP-1 , NFIV , KU80
Target XRCC5
Molecular Weight(MW) 86 kDa (note)
Application

Application

ELISA analysis of control antigen and antigen using XRCC5 antibody [5C5].

Application

FACS analysis of HeLa cells using XRCC5 antibody [5C5] (green) or a negative control (purple).

Application

ICC/IF analysis of HeLa cells using XRCC5 antibody [5C5] (green) and Alexa Fluor-555 phalloidin (red).

Application

IHC-P analysis of human tonsil tissues (left) and human colon cancer tissues (right) using XRCC5 antibody [5C5].

Application

WB analysis of (1) HeLa, (2) MCF-7, (3) A549 and (4) NIH/3T3 lysates using XRCC5 antibody [5C5].
Application Notes ELISA: 1/10000.
Additional Information
Form Liquid
Storage Instructions 4°C; -20°C for long term storage
Storage Buffer Ascitic fluid containing 0.03% sodium azide.
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