Colocalization with the ER marker calnexin (in green) revealed that mutant Kv4.3 proteins (in red) were retained in the ER, as was shown by the merged picture (in yellow).
Mouse monoclonal antibody [S75-41] to Kv4.3Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
Immunogen
Fusion protein amino acids 415-636 (cytoplasmic C-temrinus) of rat Kv4.3
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
S75-41
Host Species
Mouse
Tested Applications
ICC/IFIFIHCIPWB
We recommend a working dilution of 1ug/mL (WB), 0.1-1ug/mL (IHC/ICC), 1-10ug/mL (IF).:
Species Reactivity
HumanMouseRatXenopus
Concentration
1mg/
Purification
Protein G
Target Information
Gene Synonyms
Kcnd3 Kv4.3
Target
Kv4.3
Molecular Weight(MW)
75kDa (note)
Cellular Localization
Interaction with palmitoylated KCNIP2 and KCNIP3 enhances cell surface expression.
Application
IF
Colocalization with the ER marker calnexin (in green) revealed that mutant Kv4.3 proteins (in red) were retained in the ER, as was shown by the merged picture (in yellow).
Application Notes
We recommend a working dilution of 1ug/mL (WB), 0.1-1ug/mL (IHC/ICC), 1-10ug/mL (IF).:
Additional Information
Form
Liquid
Storage Instructions
Aliquot and store at -20 C. Avoid repeated freeze-thaw cycles.