| Product Name | L1CAM antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [1J36] to L1CAMThe protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq, Jul 2008] |
| Immunogen | Human recombinant NCAM-L1 EC domain |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 1J36 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB(1:500-1000): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | SPG1 HSAS N-CAM-L1 CAML1 MASA N-CAML1 S10 CD171 L1 cell adhesion molecule HSAS1 MIC5 L1CAM |
|---|---|
| Target | NCAM-L1 |
| Tissue Specificity | This antibody was selected for its ability to specifically detect human L1ACM |
| Application Notes | WB(1:500-1000): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
