| Product Name | Laminin alpha 5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [4C7 (2D8/33)] to Laminin alpha 5Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined. [provided by RefSeq, Jul 2008] |
| Immunogen | Purified human laminin |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | 4C7 (2D8/33) |
| Host Species | Mouse |
| Tested Applications | ELISAICC/IFIP |
| ICC/IF:1:200~1:500 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | LAMA5 |
|---|---|
| Target | Laminin Alpha 5 |
| Tissue Specificity | This antibody reacts with the globular domain of the alpha-5 chain of intact laminin. |
| Application Notes | ICC/IF:1:200~1:500 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | 0.09% Sodium Azide (NaN3) |
