| Product Name | Laminin S antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [C4] to Laminin SExtracellular matrix (ECM) surrounds and separates most tissue compartments, determines tissue architecture and dynamically interacts with its surrounding cells. The basement membrane is a part of the ECM and is composed of collagens, proteoglycans, elastin and several glycoproteins of which laminin is the most abundant. Laminins are large heterotrimeric, noncollagenous glycoproteins composed of alpha, beta, and gamma chains Dystroglycan is a major laminin receptor in muscle and epithelia, and nidogen is a high affinity laminin binding protein important for basement membrane assembly. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms. |
| Immunogen | Bovine anterior lens capsule. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | C4 |
| Host Species | Mouse |
| Tested Applications | IPWB |
| For IP: Use Protein G - Use at a dilution of 1:400. For WB: Use at a dilution of 1:200. Not suitable for use in Immunohistochemistry. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | HumanPigRatGuinea PigRabbitBovine |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | MGC128643 |
|---|---|
| Target | Laminin S |
| Cellular Localization | Basement membrane. |
| Positive Control | LS174T cells |
|---|---|
| Application Notes | For IP: Use Protein G - Use at a dilution of 1:400. For WB: Use at a dilution of 1:200. Not suitable for use in Immunohistochemistry. Optimal dilutions/concentrations should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | 10mM Phosphate-buffered saline, pH7.4 containing 0.2% BSA and 0.1% sodium azide |
