| Product Name | LAT antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to LATLinker for activation of T cells (LAT) is an integral membrane protein (36 to 38 kD), which plays an important role in linking engagement of the TCR to the biochemical events of T cell activation. LAT antibody stains thymus and peripheral lymphoid tissues such as T cell areas in lymph nodes and spleen. LAT is expressed in T lymphocytes in interstitial spaces, platelets and megakaryocytes. LAT is not expressed in B cells, macrophages, plasma cells, monocytes, epithelial histiocytes and dendritic cells. |
| Immunogen | Synthetic peptide: CHRLPGSYDSTSSDSLYPRGI, corresponding to amino acids 29-49 of Human LAT. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| ELISA (peptide): 1/100,000. IHC: Use at a dilution of 1/300. WB: Use at a dilution of 1/1000. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | LAT1 pp36 |
|---|---|
| Target | LAT |
| Tissue Specificity | Binds to a 36-40 Kd protein in normal mouse lung and heart tissue. A larger size band of approx. 40-45 Kd is seen in human tumour cell lines. |
| Cellular Localization | Cell Membrane |
| Positive Control | Human K562 and Jurkat cell lines. Mouse lung and heart lysate. |
|---|---|
| Application Notes | ELISA (peptide): 1/100,000. IHC: Use at a dilution of 1/300. WB: Use at a dilution of 1/1000. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20 to -80 °C |
| Storage Buffer | PBS, 1mg/ml BSA, 0.1% sodium azide, pH7.2 |
Data sheet for OM261248