Rabbit Polyclonal antibody to LHX8 (LIM homeobox 8)Members of the LIM homeobox gene family, such as LHX8, encode transcription regulators that share common structural features. They all contain 2 tandemly repeated cysteine-rich double-zinc finger motifs, called LIM domains, in addition to a homeodomain. The homeodomain is a DNA-binding domain, and the LIM domains are essential for regulating the activity of these molecules by interacting with other proteins. Members of the LIM homeobox gene family are required for the patterning or the specification and differentiation of different cell types during embryonic development (Zhao et al., 1999 [PubMed 10611327]).[supplied by OMIM]
Immunogen
Recombinant protein encompassing a sequence within the center region of human LHX8. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Xenopus laevis, Pig, ChickenMouse (99%), Rat (99%), Xenopus laevis (84%), Pig (100%), Chicken (98%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
Lhx7 antibody LHX8 antibody LIM-homeodomain protein Lhx8 antibody LIM/homeobox protein Lhx8 antibody LIM homeobox 8 antibody
Molecular Weight(MW)
39 kDa (note) (3)
Cellular Localization
Nucleus
Application
Application
Sample (30 ug of whole cell lysate) A: IMR32 10% SDS PAGE diluted at 1:1000
Positive Control
NT2D1 , IMR32 , U87-MG , MCF-7
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.