| Product Name | LILRB3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [9S32] to LILRB3This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | Human recombinant LILRB3. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 9S32 |
| Host Species | Mouse |
| Tested Applications | FACSWB |
| WB(1:500-2000): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PIRB LILRA6 LIR3 ILT-5 HL9 LIR-3 leukocyte immunoglobulin-like receptor subfamily B (with TM and ITIM domains) member 3 LILRB3 CD85A |
|---|---|
| Target | LILRB3 |
| Tissue Specificity | This antibody was selected for its ability to detect human LILRB3. |
| Application Notes | WB(1:500-2000): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
