| Product Name | LIME antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to LIMELIME (Lck-interacting molecule) is a new raft-associated adaptor protein involved in regulation of T cell activation by coreceptors. LIME becomes tyrosine phosphorylated after cross-linking of the CD4 or CD8 coreceptors. Phospho-LIME associates with the Src family kinase Lck and its negative regulator, Csk. Ectopic expression of LIME in Jurkat T cells results in an increase of Csk in lipid rafts, increased phosphorylation of Lck and higher Ca2+ response to CD3 stimulation. |
| Immunogen | Bacterially expressed recombinant fragment of mouse LIME. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IPWB |
| IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 32.3 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Mouse |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Protein A |
| Gene Synonyms | 54923 dJ583P15.4 72699 Lime1 LIME Q9H400 FLJ20406 609809 LP8067 2810038K19Rik |
|---|---|
| Target | LIME |
| Application Notes | IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 32.3 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 2-8ºC. Do not freeze. Do not use after expiration date stamped on vial label. |
| Storage Buffer | Phosphate buffered saline pH 7.4 containing 15mM sodium azide |
