| Product Name | Lymphotoxin beta antibody [3J26] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [3J26] to Lymphotoxin betaLymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| Immunogen | Human recombinant TNFSF3 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 3J26 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB(1:500-1000) | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | lymphotoxin beta (TNF superfamily, member 3) , TNFC , p33 , LTB |
|---|---|
| Target | TNFSF3 |
| Tissue Specificity | This antibody was selected for its ability to specifically detect human Lymphotoxin beta |
| Application Notes | WB(1:500-1000) |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
