Mouse monoclonal antibody [2H8D7] to LYNThis gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Immunogen
The immunogen corresponding to LYN expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG2
Clone Number
2H8D7
Host Species
Mouse
Tested Applications
ELISAWB
ELISA: 1/10000.
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
JTK8 , P56LYN , P53LYN
Target
LYN
Molecular Weight(MW)
56 kDa (note)
Cellular Localization
Accumulates in the nucleus by inhibition of CRM1-mediated nuclear export. Nuclear accumulation is increased by inhibition of its kinase activity. The trafficking from the Golgi apparatus to the plasma membrane occurs in a kinase domain-dependent but kinas
Application
Application
Western blot analysis using anti-LYN monoclonal antiobdy agains HL60 (1), L540 (2), SLLP-M2 (3), SEM (4) and Ramos (5) cell lysate.
Application Notes
ELISA: 1/10000.
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.