| Product Name | MAdCAM-1 antibody [17F5] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [17F5] to MAdCAM-1The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant soluble MAdCAM-1-fc fusion protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 17F5 |
| Host Species | Mouse |
| Tested Applications | ELISAFACSIHC-PWB |
| Flow Cytometry: 1/10 - 1/100 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | MADCAM1 , MACAM1 |
|---|---|
| Target | MAdCAM1 |
| Tissue Specificity | This antibody recognizes the mucin domain of MAdCAM-1. This antibody does not block the function of MAdCAM-1. |
| Application Notes | Flow Cytometry: 1/10 - 1/100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.09% Sodium Azide |
