Mouse monoclonal antibody [50] to MALT1This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant protein corresponding to amino acids 701-808 located within the C-terminal of MALT1.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
50
Host Species
Mouse
Tested Applications
IHC-PWB
Immunohistology - Paraffin: 1/25 - 1/100 Optimal dilution / concentration should be determined by the end user.
This antibody recognizes both MALT1 and the MALT1-API2 fusion protein (Murga Penas et al. 2007).
Application
Application
IHC-P analysis of human tonsil tissue using MALT1 antibody [50].
Application Notes
Immunohistology - Paraffin: 1/25 - 1/100 Optimal dilution / concentration should be determined by the end user.
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.