Mouse monoclonal antibody [7-450] to Mannose ReceptorThe recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Apr 2011]
Key Feature
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
7-450
Host Species
Mouse
Tested Applications
FACSIHC-F
Immunohistology - Frozen: 1/50 - 1/500 Optimal dilution / concentration should be determined by the end user.
This antibody recognizes human CD206, otherwise known as macrophage mannose receptor (MMR).
Application
Application
IHC-Fr analysis of human tonsil tissue using Mannose Receptor antibody [7-450].
Application Notes
Immunohistology - Frozen: 1/50 - 1/500 Optimal dilution / concentration should be determined by the end user.
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.