Application
IHC-P analysis of human liver tissue using MARCH4 antibody.| Product Name | MARCH4 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to MARCH4MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010] |
| Immunogen | Synthetic peptide sequence corresponding to a region between amino acids 300-350 of human MARCH4 - conjugated to KLH. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| Immunohistology - Paraffin: Min Dilution 5 ug/ml: |
|
| Species Reactivity | Human |
| Predicted Reactivity | zebrafish, Rat, Mouse, Horse, Dog, Chimpanzee, Chicken, Bovine |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | MARCH-IV RNF174 membrane-associated ring finger (C3HC4) 4 E3 ubiquitin protein ligase |
|---|---|
| Target | MARCH4 |
| Tissue Specificity | This antibody recognizes human Membrane-Associated Ring Finger 4 (MARCH4). |
Application
IHC-P analysis of human liver tissue using MARCH4 antibody.| Application Notes | Immunohistology - Paraffin: Min Dilution 5 ug/ml: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.05% Sodium Azide (NaN3) 0.2% Gelatin |
