Rabbit polyclonal antibody to MARCKS (phospho Ser152/156)The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008]
Immunogen
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser152/156 conjugated to KLH
Modification
p-Ser152/156
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Optimal working dilutions should be determined experimentally by the end user.: