Mouse monoclonal [1015] to MCP3This is a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix.
Immunogen
Recombinant fragment of Human MCP3 (containing 76 amino acids residues).
Key Feature
Clonality
Monoclonal
Isotype
IgG2
Clone Number
1015
Host Species
Mouse
Tested Applications
ELISAWB
ELISA: Use at an assay dependent dilution. WB: Use at a concentration of 0.5 - 2 μg/ml (allows visualization of 0.1 μg/lane of human MCP3). Predicted molecular weight: 11 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Protein G
Target Information
Gene Synonyms
Monocyte chemoattractant protein3 SCYA6 MCP3 Monocyte chemotactic protein 3 CCL7 SCYA7 FIC NC28 Chemokine CC Motif Ligand 7 Monocyte chemoattractant protein 3 Chemokine CC Motif Ligand7 Small inducible cytokine A7 MARC Monocyte chemotactic pro
Target
MCP3
Tissue Specificity
This antibody reacts with natural and recombinant human MCP3. It does not show any cross reaction with other human cytokines or growth factors tested such as IL1 beta, IL8, MCAF, SAA and EGF.
Cellular Localization
Secreted
Light Chain Type
kappa
Application Notes
ELISA: Use at an assay dependent dilution. WB: Use at a concentration of 0.5 - 2 μg/ml (allows visualization of 0.1 μg/lane of human MCP3). Predicted molecular weight: 11 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.