Rabbit polyclonal to MDC1MDC1 participates in the early response to DNA damage. It is thought to be a member of the BRCT (BRCA1 C-terminus) super family of nuclear proteins. It contains an N-terminus forkhead-associated (FHA) motif, two C-terminus BRCT motifs and 13 internal repetitions of a 41 amino acid sequence.
Immunogen
Synthetic peptide: RQESDKNGESASPERDRE , corresponding to amino acids 871-888 of Human MDC1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: Use at a dilution of 1/200 - 1/1000. Detects a band of approximately 220 kDa (predicted molecular weight: 250 kDa). Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Protein G
Target Information
Gene Synonyms
DKFZp781A0122 KIAA0170 MGC166888 NFBD1
Target
MDC1
Cellular Localization
Nucleus
Application
Application
Western blot analysis of NFBD1 in 30 ugs of Jurkat cell lysate at 1:1000 dilution.
Positive Control
Jurkat whole cell lysate
Application Notes
WB: Use at a dilution of 1/200 - 1/1000. Detects a band of approximately 220 kDa (predicted molecular weight: 250 kDa). Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.