Mouse monoclonal [HMB45] to Melanoma associated antigenThis antibody reacts with an antigen present in cutaneous melanocytes, prenatal and infantile retinal pigment epithelium and melanoma cells.This antibody reacts with melanomas and tumors showing melanoma/melanocytic differentiation. It reacts with junctional and blue nevus cells. Non-melanocytic cells do not react with this antibody.
Immunogen
Extract of pigmented melanoma metastases from lymph nodes.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
HMB45
Host Species
Mouse
Tested Applications
ICC/IFIHC-PWB
For IF: Use at an assay dependent dilution. For IHC-P: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.
Species Reactivity
Human
Concentration
0.2mg/ml
Purification
Affinity purified
Target Information
Target
Melanoma associated antigen
Cellular Localization
Cytoplasmic
Light Chain Type
kappa
Application Notes
For IF: Use at an assay dependent dilution. For IHC-P: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
Storage Buffer
PBS, pH 7.4, containing 0.2% BSA and 0.09% sodium azide