Rabbit polyclonal antibody to MFSD2BMultidrug transporters, such as MFSD2B, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2B is closely related to MFSD2A, which is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting, playing a major role in the induction of MFSD2A expression during adaptive thermogenesis. Unlike MFSD2A, MFSD2B is expressed in few tissues and at relatively low levels, and is not induced during fasting, suggesting that MFSD2B may play other roles.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
MFSD2B Major facilitator superfamily domaincontaining protein 2B Major facilitator superfamily domaincontaining protein2B Major facilitator superfamily domain-containing protein 2B
Target
MFSD2B
Tissue Specificity
This antibody is specific for MFSD2B
Application
Application
Western blot analysis of MFSD2B in rat lung tissue lysate with MFSD2B antibody at (A) 1 and (B) 2 ug/ml.