Application
Western blot analysis of MFSD2B in rat lung tissue lysate with MFSD2B antibody at (A) 1 and (B) 2 μg/mL.| Product Name | MFSD2B Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | MFSD2B Antibody: Multidrug transporters, such as MFSD2B, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2B is closely related to MFSD2A, which is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting, playing a major role in the induction of MFSD2A expression during adaptive thermogenesis. Unlike MFSD2A, MFSD2B is expressed in few tissues and at relatively low levels, and is not induced during fasting, suggesting that MFSD2B may play other roles.1) Fluman N and Bibi E. Bacterial multidrug transport through the lens of the major facilitator superfamily. Biochim. Biophys. Acta.2009; 1794:738-47. |
| Immunogen | MFSD2B antibody was raised against a 15 amino acid synthetic peptide near the center of human MFSD2B. The immunogen is located within amino acids 240 - 290 of MFSD2B. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| MFSD2A antibody can be used for detection of MFSD2A by Western blot at 1 - 2 μg/mL. | |
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MFSD2B |
|---|---|
| Alternative Names | MFSD2B Antibody: Major facilitator superfamily domain-containing protein 2B |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Mouse: (80%) |
| Entrez Gene | 388931 |
|---|---|
| Protein Accession | NP_001073942 |
Application
Western blot analysis of MFSD2B in rat lung tissue lysate with MFSD2B antibody at (A) 1 and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1462 - Rat Lung Tissue Lysate |
|---|---|
| Application Notes | MFSD2A antibody can be used for detection of MFSD2A by Western blot at 1 - 2 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | MFSD2B antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | MFSD2B Antibody is supplied in PBS containing 0.02% sodium azide. |
